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Ray Greek MD and Mark Rice MD’s article cited in the journal ‘Annals of Intensive Care’

Ray Greek MD and Mark Rice MD’s article Animal Models and Conserved Processes (Theoretical Biology and Medical Modelling 9/1/40)  has been cited in a paper published by Bara and Joffe: The methodological quality of animal research in critical care: the public face of science (Annals of Intensive Care, 4, 26): excerpt below:

These, and other similar findings, suggest that a systems biology approach to the nonlinear complex chaotic dynamics of mammalian organisms in which responses are extremely sensitive to initial conditions (the genome and its epigenetic regulatory mechanisms) explains the lack of translation. By this explanation, in principle, AR findings will not predict human responses.